Eat anti-inflammatory drugs can not sleep, may be the side effects of drugs, some anti-inflammatory drugs may have a certain excitatory effect on the brain, can cause patients with sleep dysfunction, the patient may have insomnia, clinically common quinolones, such as levofloxacin and ciprofloxacin, if the patient has a seizure is not generally recommended to apply. Patients with cerebrovascular disease, such as massive cerebral infarction and massive cerebral hemorrhage, are often combined with lung infection, urinary tract infection and decubitus ulcer infection. Anti-inflammatory drugs should be applied to carry out anti-inflammatory treatment, mainly cephalosporin antibiotics, tinidazole or metronidazole if necessary, quinolones are not recommended.