Duodenal tumors can be roughly divided into benign and malignant. If benign duodenal tumors are detected and treated timely, they usually will not affect the life expectancy, while if malignant duodenal tumors are detected, they will affect the life health. However, because the survival period of patients is also affected by other factors, therefore, it should not be judged only by the nature of tumor.1. Benign duodenal tumor: If it is benign duodenal tumor, such as adenoma, lipoma, smooth muscle tumor, neurofibroma and hemangioma, etc., it can be treated by lumpectomy or minimally invasive surgery with imaging intervention, and the prognosis is good, and the survival period can reach several decades. Some patients may suffer from gastrointestinal bleeding, intestinal obstruction and other diseases if they are not treated timely, requiring emergency treatment, and some patients may not be completely cured; 2. Duodenal malignant tumors: early symptoms are not obvious, and the five-year survival rate is high after active treatment. Since duodenal examination is more complicated to confirm the diagnosis, many malignant tumors of duodenum are found late and the prognosis is relatively poor. If the examination is found at an advanced stage, the survival period can be 1-2 years after active treatment, but without any treatment, the survival period is greatly shortened, even only about 1 month. In daily life, patients need to follow medical advice for active treatment and regular follow-up. If abnormal symptoms occur, such as obstruction or black stool, they need to seek immediate medical attention to avoid adverse conditions.