Positive hepatitis B E antigen generally indicates that the body has a high replication capacity for the hepatitis B virus. This condition needs to be analyzed in combination with other indicators, and requires close testing of hepatitis B DNA, liver function, abdominal ultrasound, and methemoglobin. When liver function appears significantly abnormal, timely antiviral therapy is needed, along with combined liver-protective and enzyme-lowering therapy, such as oral tenofovir or entecavir or propofol tenofovir. If you are eligible for interferon antiviral therapy, you can also choose interferon antiviral therapy. If the liver function is normal, other indicators are normal, there is no cirrhosis of the liver, under 30 years old temporarily do not need treatment, regular review, adequate rest, maintain good sleep.