Patients with diabetes develop numbness in the hands and feet, mainly as a symmetrical numbness in the feet and hands, a medical term for a sock-like or glove-like sensation. Other patients may experience a burning tingling sensation at the ends of their hands and feet, which is sometimes more pronounced at night and can seriously affect their sleep. As the numbness in the hands and feet progresses further, the pain and temperature sensation in the hands and feet will be significantly diminished, and the main symptoms will be coldness in the hands and feet, which are some of the symptoms of advanced diabetic peripheral neuropathy.