I. OBJECTIVE Vulvar cancer is a malignant tumor originating from the skin, mucosa and affiliated organ ducts of the vulva and vestibular gland ducts, etc. It often occurs in middle-aged and old-aged women and accounts for about 3%~5% of the malignant tumors of the female reproductive tract, of which primary squamous carcinoma of the vulva is predominant and accounts for more than 90%, and secondary malignant tumors are rare. The treatment of vulvar cancer is mainly based on surgery [1], and the surgery generally adopts radical vulvovaginal surgery, i.e., vulvovaginal wide excision plus inguinal and or pelvic lymph node dissection, and the 5-year generative rate using this surgery is about 70%, but the skin lesions are large, the suture tension is high, and the incision is easy to be infected [2], in addition to the fact that the surgical incisions are adjacent to the vulva, the urethra, the anus, the rectum, which makes it very easy to contaminate the wounds and the patients with poorer resistance at the old age, so the Reasonable and effective perioperative care is particularly important for patients to safely pass the infection level after surgery, for also after surgery some patients need to supplement radiotherapy and chemotherapy to provide a guarantee of smooth progress. Methods II. Surgical execution, skin preparation was changed to first cut the hair with sterilized scissors and then shaved with an electric razor, and the postoperative incision was changed to open and irradiated with a specific electromagnetic wave TDP every day on the 4th day of the incision; the control group will still set the preoperative skin preparation time to be executed 1 day before the surgery and shaved with a manual razor, and the postoperative incision was still covered with a traditional dressing on the 4th day of the incision. In addition to the skin preparation time, method and incision care method, the experimental group was in the same environment of the hospital room, the application of antibiotics and other treatment and care methods as the control group. Third, care 1, preoperative skin preparation time and skin preparation method improvement according to the national standards, the traditional shaving operation, even if the operation is very skillful will damage the skin, resulting in skin scars invisible to the naked eye, while the integrity of the skin in preventing bacterial infections has an extremely important role in the skin, the skin of the small scratches will become a place for bacterial growth and reproduction, but also can cause bacterial migratory growth. It is also pointed out that the purpose of preoperative skin preparation is to reduce the rate of postoperative incision infection, first of all, attention should be paid to the choice of skin preparation methods, the key is to clean the bath must be clean, to reduce the temporary resident bacteria, to remove the long-lived bacteria, in order to reduce the rate of infection of the surgical incision, if it does not involve the surgical area of the hair can be not removed, if you want to remove the hair, the removal of hair, remove the time away from the operation time the shorter the better, and to cut the hair is the best. 2.Pre-operation intestinal, vaginal and vulvar preparation 1 week before the operation do not eat multi-fiber food, 3 days before the operation into a non-dregs diet, 1 day before the operation into a liquid diet, the night before the operation or the morning of the operation to clean the enema; 3 days before the operation began to carry on the vaginal douche and vulvar scrubbing, 2 times / d, and the morning of the operation and then carry on the vaginal douche and vulvar scrubbing for 1 time. 3.Preoperative prophylactic antibiotic applicationPreoperative prophylactic use of antibiotics has become one of the auxiliary measures to solve the problem of preventing infections at the site of surgical incision, which can make the surgical incision exposed to local tissues to reach a sufficient concentration of drugs to kill the bacteria invading the incision in the course of the operation, and require the use of antibiotics in the preoperative period (before the surgical incision of the skin) within 0.5-2h or at the beginning of the anesthesia, therefore, this hospital has already practiced the preoperative administration of medication by the original ward nurse Therefore, our hospital has changed the preoperative medication from ward nurses to operating room nurses, so that the time of preoperative prophylaxis can be well mastered, thus achieving the best effect of prophylaxis. 4. The environment of the ward should keep the ward clean and air circulation, open the window for ventilation every day, the number of visitors should be controlled, the air should be sterilized by disinfector for 1h every day, the floor of the room and the surface of the articles should be sterilized by wet disinfection, and the floor should be mopped with chlorine mop every day and wiped with chlorine mop, and the treatment of vulvar cancer is mainly based on surgery, and the healing of the incision is delayed due to the large scope of tissue resection, high bleeding, and easy to be infected in the postoperative period, which influences the patients to need the supplemental treatment in the postoperative period. By changing the time and method of preoperative preparation, the nurse firstly cuts the hair with sterilized scissors, then shaves and disinfects it with electric razor, and after shaving, the skin preparation area is scrubbed with 0.05% iodophor solution, and the non-surgical area is not cut the hair, which avoids the skin damage caused by the traditional skin preparation and skin scars invisible to the eyes, and maintains the integrity of the skin in the surgical area to avoid the invasion and migration of bacteria, but this method is more complicated than the traditional method, which is more effective than the traditional method. However, this method is more time-consuming than the traditional skin preparation, which undoubtedly increases the workload of nurses. This problem has been solved. Conclusion Through the above all-rounded nursing care for patients with vulvar cancer surgery, the infection rate of postoperative incision was effectively reduced, and the patients could get through the perioperative period smoothly, which laid a solid foundation for the patients to complete the subsequent treatment.