When a person is infected with herpes simplex virus, the virus will gather in the soft tissues around the mouth, and once the immune function is disrupted or low, the toxicity of the herpes simplex virus will rise, causing blisters around the lips and even inside the mouth. When a person is in a cold and flu, menstrual period or work stress, long-term travel or stay up late, this state of immune function exists in varying degrees of disorder or even low, herpes around the mouth is easy to appear. When herpes appears around the mouth after the antiviral treatment, you can take oral antiviral oral solution, Banlangen granules, Ganciclovir, Acyclovir and other drugs, you can also apply local acyclovir ointment on the herpes for local treatment. At the same time, you should avoid spicy and irritating foods in your diet, drink more water, ensure balanced nutrition, and get enough sleep to enhance your body’s immune function.