Urethral atrophy may be caused by endocrine disorders during menopause, which is related to the decrease of estrogen level. It can be treated by general treatment, medication (levofloxacin, etc.), surgery and other methods under the guidance of doctors. 1. General treatment: patients need to strengthen the diet and nutrition, do not be too picky about food, diet, eat more rich food, such as eggs, lean meat, fresh vegetables, etc., and pay attention to the pubic hygiene in life, to avoid too much moisture in the local area. 2. Drug treatment: the disease is mainly related to estrogen secretion, recurrent urethritis and other factors, need to be treated according to the condition, if it is estrogen secretion is insufficient, you can use estrogen drugs, such as combining estrogen cream, pentynyl estradiol, etc.; if it is related to urethritis, you can through the levofloxacin, cephalexin and other drugs treatment. 3. Surgery: For patients with severe urethral atrophy, surgery can be given for treatment, such as urethral dilatation, urethroplasty and so on. It is recommended that patients go to the regular hospital in time, under the diagnosis of the doctor, according to the patient’s specific condition, to take targeted treatment, follow the doctor’s instructions to use drugs.