Sleeping at night with rumbling in the trachea with difficulty in expiration can be seen in asthma, acute exacerbation of chronic bronchitis, acute left heart failure and other diseases. 1. Bronchial asthma: As the vagus nerve is excited at night, the airway reactivity increases, and bronchospasm may occur, showing symptoms such as wheezing, dyspnea and rumbling. Treatment can use bronchodilators such as salbutamol, glucocorticoids such as budesonide and other nebulized inhalation to relieve symptoms. 2. Acute exacerbation of chronic bronchitis: when there are triggers such as infections, it can lead to acute exacerbation of chronic bronchitis, which in turn causes increased respiratory secretions, and the emergence of airway sound with dyspnea during sleep. The first treatment is to remove the causative factors, can use amoxicillin, cefoperazone and other antibiotics to fight infection, and at the same time, use aminoglutethimide and other cough and phlegm treatment. 3. Acute left heart failure: patients with cardiac insufficiency, when lying down at night, the return blood volume increases, the heart load is enhanced, which may lead to a sharp decline in the ejection function of the heart, resulting in pulmonary stasis, resulting in dyspnea with rales. Treatment is taken to improve symptoms with oxygen, digoxin cardiotonic, furosemide diuretic and other treatments. Dyspnea with rales at night can also be caused by other diseases. It is recommended to consult a doctor in time, complete the examination, clarify the cause of the disease, and follow the doctor’s instructions, so as not to delay the condition.