The foreskin glans inflammation for a long time does not get better, accompanied by penile and urethral pain, is a symptom caused by mucosal injury, the specific treatment program mainly includes drug treatment, physical therapy, surgical treatment, and daily care and so on. 1. Drug treatment: according to different types of inflammation, we need to choose to do drug anti-inflammatory treatment, bacterial or mycoplasma and other pathogenic infections can do drug sensitivity test, according to the type of pathogen application of antibiotics, commonly used drugs, including azithromycin, etc.; part of the population is allergic to the factors caused by the application of hydrocortisone and so on. 2. Physical therapy: some lesions lead to long-term mucosal recovery, can be applied to the way of freezing. 3. Surgical treatment: long foreskin or prepuce is easy to cause the corresponding condition, can do circumcision surgery to improve. 4. Daily care: usually pay attention to personal hygiene, pay attention to ensure that the local skin dry, avoid repeated stimulation and friction, you can apply potassium permanganate solution rinse. The foreskin glansitis for a long time does not get better, accompanied by penile and urethral pain, need to consult a doctor in a timely manner, after diagnosis of the cause of the disease in the clinician under the guidance of standardized treatment, to avoid delays in the condition.