With the growth of age, many people have the phenomenon of sagging corners of the mouth, sagging corners of the mouth not only directly affects the person’s facial expression and appearance image, but also destroys the overall beauty of a face. In general, the cause of sagging corners of the mouth is divided into two points, one is the external factors, caused by long-term bad habits; the second is the internal factors, that is, with the growth of age, the person’s facial skin relaxation, resulting in sagging corners of the mouth. The improvement method has hyaluronic acid injection corner of the mouth lift, through the corner of the mouth injection hyaluronic acid to fill lift the corner of the mouth, in addition can be injected at the same time in the corner of the descending mouth muscle appropriate amount of botulinum toxin, so as to block neuromuscular conduction, to achieve the purpose of relaxing the muscle, the corner of the mouth naturally shows a rising trend. For sagging corners of the mouth with more serious marionette lines, filler injections of marionette lines are needed because the local depressions are not well corrected and the sagging corners of the mouth will easily reappear.