Gallbladder wall thickening of 4mm is usually removed surgically. Gallbladder wall thickening of 4mm is considered to be caused by chronic cholecystitis, obstructive cholecystitis, metabolic cholecystitis and other diseases, usually abdominal distension, right upper abdominal discomfort, loss of appetite and other symptoms, such as if the development of a long period of time may cause progressive thickening of the gallbladder wall, the gallbladder loses its function or even malignant transformation of the gallbladder, so it is necessary to surgical resection treatment. Patients should go to the hospital in time, under the guidance of the doctor for cholecystectomy, and after the operation should pay attention to avoid greasy food, to light and nutritious food, and pay attention to appropriate exercise, keep the wound clean and dry after the operation. It is recommended that patients go to the hospital in time for examination and treatment, pay attention to diet and hygiene as well as daily rest, and exercise appropriately.