Running throat pain may be related to water evaporation, inflammatory reaction, temperature stimulation. 1. Moisture evaporation: when running, the need for oxygen increases, only breathing through the nose can not meet the amount of oxygen needed, so it will use the mouth to breathe. This will lead to the air into the mouth will take away part of the moisture, can not moisturize the throat, so it will lead to dry and sore throat. 2. Inflammatory reaction: turbid or dry air enters the throat during running, stimulating a transient stress reaction locally and releasing inflammatory factors to stimulate the nerve endings to appear pain. 3. Temperature stimulation: the body circulation is accelerated, water evaporation and cooling accelerated, exhaling cold air will stimulate the dry mucous membrane of the throat to cause pain. Running can be timely and appropriate supplemental water, not running in bad weather, or can reduce the occurrence of sore throat.