Ichthyosis is a group of hereditary skin diseases characterized by abnormal keratinization and dry skin with fish scale scales. In treatment, it is mainly symptomatic treatment to relieve abnormal keratinization, mainly topical medication, emollients, moisturizers, keratin exfoliators can be used, such as 10%-20% urea cream, 3%-15% lactic acid ointment, 40%-60% propylene glycol solution can increase the degree of skin hydration, topical vitamin A acid preparations also have a certain effect. For severe cases, oral retinoic acid, isotretinoin or avea can also be effective.