The diagnosis of thalassemia is mainly based on hemoglobin and blood cell examination in the blood, while newborns are usually drawn plantar blood for examination due to the thin blood vessels, so the detection of thalassemia by plantar blood is usually more accurate.
The diagnostic criteria for thalassemia are mainly small red blood cells and low pigmentation in routine blood tests, and hemoglobin is analyzed and there is a decrease in the osmotic fragility of red blood cells. Since thalassemia is a hereditary disease, genetic testing can be performed by restriction endonuclease profiling, polymerase chain reaction and other methods if necessary.
Generally speaking newborn heel blood tests for thalassemia are relatively accurate, and if thalassemia is suspected, you should seek further medical examination and diagnosis and treatment.