Many hypertensive patients take oral antihypertensive drugs for a period of time, and then find that their penis can not be erected normally, the patient is very anxious and confused, so many patients immediately stop the antihypertensive drugs. Such an approach is wrong. The right approach should be to face the reality, not just stop or change the drug, and not because of shame and random self-treatment, should follow the following recommendations to actively respond: 1, hypertension can lead to small-vessel atherosclerosis: long-term poor control of blood pressure will accelerate vascular endothelial damage, which leads to narrowing of the arterial lumen, slowing blood flow, resulting in insufficient filling of the penile corpus cavernosum, resulting in erection insecurity or inability to get an erection (impotence). So patients with poor blood pressure control, should actively control blood pressure, so that blood pressure fluctuations in the ideal level; 2, antihypertensive drugs can lead to impotence: blood pressure class and its compound preparations (such as blood pressure, blood pressure, Anda blood pressure, Jing, compound descending tablets, antihypertensive spirit, etc.), β-blockers (such as the heart, Metoprolol, Liuramine benzathine, etc.), diuretics and other antihypertensive drugs can lead to sexual function decline. If impotence is caused by antihypertensive drugs, you should choose a suitable antihypertensive drug for yourself after comprehensive consideration by your doctor. It is not advisable to stop the medication abruptly because doing so can cause the withdrawal syndrome of a sharp increase in blood pressure, which is very prone to serious consequences. The correct method is to gradually reduce the dosage and stop the medication slowly. 3. Other drugs can also cause impotence: such as sedatives, antidepressants, anticholinergic agents, H2 receptor antagonists, 5a reductase inhibitors, etc. If the above drugs are found to cause impotence, after the doctor weighs the pros and cons, the medication can be changed or discontinued according to the doctor’s recommendation. In conclusion, once impotence occurs in hypertensive patients, they should actively seek medical advice, analyze the causes of impotence, correctly weigh the pros and cons, and reasonably adjust their treatment.