Progesterone in women is secreted due to ovarian function, as the ovaries secrete estrogen, progesterone and a small amount of androgens, and when there is low progesterone, there are more reasons for this. When the ovarian function is reduced, it will cause low progesterone, which will cause confusion in the menstrual cycle and will affect the menstrual changes and the quality of the follicles, which will affect pregnancy and may cause preterm abortion after pregnancy. Second, it is the lack of progesterone due to luteal insufficiency, which can cause a low progesterone at this time. Third, when there is an endocrine hormone imbalance, this will cause low progesterone due to hormonal disruption. When there is low progesterone, there may be abnormal bleeding and prolonged menstrual cycle, so go to the hospital as soon as possible for blood test, endocrine hormone six including anti-Mullerian hormone to determine, according to the situation can be treated with oral medication.