Multiple ischemic foci in the brain with cerebral white matter degeneration means that the capillaries or small arteries inside the brain are in the state of atherosclerosis, and the blood flow to the brain is slow and cannot pass through or localized blood vessel blockage leads to ischemia and hypoxia of brain tissues, which causes degeneration and necrosis of brain cells. At the time of examination, some patients may have no clinical symptoms, while some may have symptoms of insufficient blood supply to the brain such as dizziness, headache and nausea. Cerebral white matter is a kind of neural structure in the brain, and when white matter degeneration occurs in the brain, patients may have clinical manifestations such as cognitive, sensory, and mental disorders. Patients should pay good attention to blood pressure, blood lipids, blood sugar, and if there are corresponding underlying diseases, they must be controlled with medication. On this basis, oral aspirin enteric-coated tablets can be used for anti-platelet aggregation, and atorvastatin calcium tablets can be used to regulate lipids and stabilize plaques, and regular rechecks can be performed. It is recommended that patients with multiple ischemic foci in the brain accompanied by cerebral white matter degeneration should consult a doctor in time, and the doctor will make corresponding treatment according to the patient’s condition.