The presence of crystals in the lungs, which can be observed on chest CT films, is often referred to clinically as calcified foci of the lung, also called calcified granulomas of the lung. The formation of calcified granulomas of the lung is usually due to infections that can arise from bacterial infections, such as tuberculosis, and calcified granulomas can also form from fungal infections, such as histoplasmosis or aspergillosis, and non infectious causes, including nodular disease and Wegener’s granulomatosis. Most calcified granulomas are benign and may also be cancerous or tumorous. If the calcified granuloma is benign, it usually does not require treatment, but if there is an active infection or other condition causing the granuloma to form, treatment is indicated. If active bacterial and fungal infections are present, they are treated with antibiotics or antifungal drugs, and to control inflammation, also with Glucocorticoids and other immunosuppressive drugs are used for treatment.