Pseudomonas aeruginosa is a gram-stain negative bacillus, widely distributed in the environment of the natural world, can be present in the intestinal tract, respiratory tract and surface skin tissues of healthy people, because of the green color of the pus and exudate after infection, so it is also known as Pseudomonas aeruginosa, which is a more common conditionally pathogenic bacteria in the clinic. Pseudomonas aeruginosa infection can occur in any tissue and part of the human body, often causing surgical incision, burn tissue infection, but also can lead to otitis media, keratitis, urethritis, gastroenteritis, endocarditis, pus thorax, bacteremia, septicemia and so on. Pseudomonas aeruginosa is resistant to most antibiotics and can rapidly produce drug-resistant mutations, and effective antibiotics should be selected according to drug sensitivity tests during treatment. Patients with Pseudomonas aeruginosa infection should seek medical attention in time, and be treated by a professional physician who combines drug sensitivity tests to select effective drugs.