If an elderly person develops facial puffiness, the following factors should be considered: First, the clinical symptoms and reactions of facial puffiness, heat, and pain will be present if infections are considered, such as bacterial, viral, or other pathogenic microbial infections, which lead to the development of facial cellulitis in the elderly. Secondly, if the elderly have chronic hypothyroidism or hypoadrenalism, they will also have clinical symptoms of puffiness and edema of the frontal face. Third, if the elderly have hypometabolism or serious malnutrition, this will lead to facial swelling due to hypoproteinemia. Fourth, if the elderly are in chronic renal insufficiency for a long time, the patient will have swelling of the face due to large amount of proteinuria and hypoproteinemia. Fifth, if the elderly have chronic cardiac insufficiency, especially in chronic right heart failure, they will also have this clinical manifestation.