If estradiol valerate tablets are used to treat ovulatory bleeding, they should be started on the 12th day of menstruation and taken for 7 consecutive days to effectively treat ovulatory bleeding. If it is used for the treatment of artificial cycle, it should be started on the 5th day of menstruation and taken for 21 consecutive days, which means that it should be continued after ovulation, so it depends on what kind of disease it is used for, and it should be used accordingly only under the guidance of a doctor. This drug has indications and contraindications. If you have a tendency to thrombosis, breast cancer or other gynecological diseases, such as uterine fibroids, it is not recommended to take this drug for the corresponding treatment, so as not to cause greater impact, but to follow medical advice.