If the insomnia is simple and chronic, it usually does not directly lead to death, but it has a significant impact on physical health. If long-term insomnia leads to severe anxiety and depression, there is a possibility of indirectly causing death. Long-term insomnia can cause the body’s immunity to be constantly reduced, and the ability to resist diseases gradually decreases, at which time it may aggravate other diseases or trigger the onset of existing diseases, such as hypertension, diabetes, gastrointestinal diseases, cancer, etc., especially for the elderly. In addition, long-term sleep deprivation disrupts the body’s biological clock and accelerates aging. Men with prolonged insomnia will suffer from mental depression, physical weakness and a serious decline in sexual function, while women with long-term insomnia will suffer from early menopause, skin pigmentation and fatigue. Long-term sleep deprivation will not allow the brain to get sufficient rest, will accelerate the death of brain cells, so that people in a trance, slow reaction, memory loss, seriously affect the brain’s creative thinking, resulting in work, learning efficiency. Long-term insomnia is more serious harm is to lead to depression, anxiety and other bad mood, severe anxiety, depression patients may have the idea of light, which may lead to indirect death.