Aspirin is not a drug that cannot be stopped once taken. The decision depends on the purpose of the drug and whether side effects occur. If aspirin is used as a platelet aggregation inhibitor, it should not be stopped once it is taken, but if it is used as an antipyretic or antirheumatic drug, there is no strict rule that it cannot be stopped. Aspirin plays an important role in the treatment of coronary heart disease, acute myocardial infarction, transient cerebral ischemia and other diseases, inhibiting platelet aggregation and effectively alleviating the further development of the disease. For such patients, once they take aspirin, they cannot stop, because after stopping the drug, the body’s platelet activity will return to the level before taking the drug, and there is a risk of inducing the formation of blood clots again. If side effects occur, such as bleeding from the fundus, gum bleeding, etc., carotid ultrasound should be performed before stopping the medication to observe the plaque condition at the infarct site, and make a comprehensive analysis with bleeding and other conditions, weigh the pros and cons, and let the doctor decide whether to carry out alternative therapy or continue taking the medication. While taking aspirin, it is necessary to observe for side effects such as bleeding from the fundus of the eyes as well as bleeding gums, black stools and nasal bleeding, and to review them in a timely manner. It is usually recommended that aspirin be taken with food and water to avoid increasing the risk of local bleeding. However, if aspirin enteric tablets are taken, they need to be taken on an empty stomach. If you experience dizziness, headache, nausea, or even liver or kidney impairment and hemolytic anemia while taking aspirin, discontinue the medication immediately and seek prompt medical attention.