The causes of melasma are complex, so it is important to find the causes as much as possible and give appropriate treatment for them. Sun protection is an indispensable measure to treat melasma. The following is a brief introduction of systemic treatment and local treatment.1. Systemic treatment: including oral and intravenous injection of large doses of vitamin C. Vitamin C can reduce dopaquinone to dopa or prevent dopa from oxidizing dopaquinone to inhibit the formation of melanocytes, so it has the effect of removing spots. Secondly, Chinese herbal medicine treatment, mainly to dredge liver and Qi, strengthen spleen and kidney, activate blood circulation and remove blood stasis, such as Liu Wei Di Huang Wan, Yi Yao Wan, etc. 2, local treatment: such as tyrosinase inhibitors, hydroquinone, which is more common in clinical practice, also called Qian Bai. Other, such as 2%-4% tric acid and so on; and some reducing agents, vitamin C local iontophoresis therapy; and inhibit the transformation of melanosomes, such as nicotinamide can also accelerate the renewal of the skin; with fruit acid peeling therapy; and physical therapy, such as short pulse carbon dioxide laser pulse dye laser and so on, their principle of action is to destroy the melanin particles in the upper dermis, for the treatment of hyperpigmentation There are also liquid nitrogen, liquid oxygen and other low boiling point media freezing caused by superficial second-degree frostbite of the epidermis, thereby healing the skin to achieve the purpose of repair. In China, there are also applications of skin micro-ecological system, such as skin care cream, which are reported to treat melasma. Therefore, the treatment of melasma should be different from person to person, and we should go to a regular hospital to clarify the cause of the disease, and target individualized treatment for the cause of the disease.