The commonly used methods for removing forehead wrinkles are hyaluronic acid and botulinum toxin injections. Botulinum toxin, as a biotoxin agent with wide clinical application, can selectively block the activity of the frontal muscle after injection into the human body, so that the power of the frontal skin wrinkles can be reduced and the effect of removing the headline can be achieved. But botulinum toxin injection to remove the headline also has certain risks, as follows: 1, skin bruises: skin bruises mostly due to blood exudation, generally do not need special treatment, 2-3 weeks can be self-receding; 2, botulinum toxin to remove the headline, the patient can not be laughing or open mouth and other actions within 1 month, so as not to cause facial skin strains; 3, within a short period of time after surgery, the patient may appear pain, edema Some patients may have complications such as incomplete closure of the orbicularis oris muscle, dry eye syndrome, swallowing difficulties, etc.; 4, a small number of allergic reactions, and injection symptoms of poisoning, affecting life safety, usually need to be observed in the hospital for 15 minutes after injection, if there is no discomfort before leaving the hospital. In addition, after the injection of Botox, patients should pay attention to drink more water to prevent the effect of Botox toxicity. If toxic reactions such as weakness, fever, or generalized itching occur, patients must go to the hospital in time for examination and treatment according to the doctor’s instructions.