Side effects of rabies vaccination for 3-year-olds include fever, localized redness and swelling, malaise, loss of appetite, skin rash, allergic reactions, etc. However, the mortality rate of rabies is 100%, so it is necessary to receive rabies vaccination in time for exposure. Rabies vaccine is an inactivated vaccine, adverse reactions are rare, according to the instructions for use of the drug, common adverse reactions include redness and swelling at the site of vaccination, fever, malaise, muscle pain, vomiting, abdominal pain, etc. Generally no special treatment is needed, and can be relieved by itself, rare occurrence of more than moderate fever, allergic rash, anaphylactic shock, and anaphylactic purpura, which requires medical treatment. Rabies is the infectious disease with the highest morbidity and mortality rate, and the mortality rate after the onset of the disease is almost 100%. Therefore, exposure requires timely use of rabies vaccine as prescribed by the doctor, and rabies virus immunoglobulin to prevent infection if necessary.