Immunity disorders may lead to immune hemolytic anemia, such as: autoimmune hemolytic anemia, warm antibody autoimmune hemolytic anemia, cold antibody autoimmune hemolytic anemia, drug-induced immune hemolytic anemia and so on.
1. Autoimmune hemolytic anemia: It refers to the hemolytic anemia caused by B-lymphocyte immunoregulation disorder in the body, which produces autoantibodies and complements and binds to the red blood cell membrane and accelerates the destruction of red blood cells through antigen-antibody reaction.
2. Warm antibody type autoimmune hemolytic anemia: the antibody is mainly IgG, the most active at 37℃, incomplete antibody, adsorbed on the surface of red blood cells. Sensitized erythrocytes are mainly destroyed in the monocyte-macrophage system, and extravascular hemolysis occurs, thus autoimmune hemolytic anemia occurs.
3. Cold antibody-type autoimmune hemolytic anemia: the antibody is mostly cold agglutinating IgM, which is a complete antibody, and the maximum reactivity is shown at 0-5℃, which is cold antibody-type autoimmune hemolytic anemia.
4. Drug-induced immune hemolytic anemia: certain drugs such as anti-complement monoclonal antibody can control hemolytic symptoms, but there is a possibility of breakthrough hemolysis, which in turn leads to anemia.
To sum up, immune disorder can lead to anemia, so when you suspect immune disorder or anemia, you should consult the doctor in time to avoid delaying your condition.