It is possible to apply biologics in the early stages of psoriasis. Psoriasis, commonly known as psoriasis, is a chronic inflammatory skin disease. The onset of the disease is related to many factors, related to genetic factors, mental factors, infectious factors and so on. The main manifestation is red papules or plaques with thick scales. When the initial symptoms of psoriasis are not serious, it is usually treated with topical medication, and the medication with the least adverse reaction can be chosen as prescribed by the doctor, such as glucocorticoid preparations and vitamin D3 derivatives. Psoriasis biologics is a new treatment in recent years, which can rapidly inhibit immune inflammation and stop the progression of the disease. The more commonly used biologics in clinical practice include drugs such as adalimumab and infliximab. Biologics are mainly used for moderate and severe psoriasis, but mild psoriasis can also be treated with biologics. Biologics have fewer side effects and maintain their effectiveness for a longer period of time. However, biologics are much more expensive compared to other medications. If there is a case of psoriasis early want to use biological agents, it is recommended to go to the hospital, under the guidance of the doctor treatment.