Hepatitis B major triple-positive, that is, positive for hepatitis B surface antigen (HBsAg), hepatitis B e antigen (HBeAg) and hepatitis B core antibody (anti-HBC), reflects the immune status of the virus when it is present in the body. Positive hepatitis B surface antigen: Hepatitis B surface antigen can be positive after 2 weeks of hepatitis B virus (HBV) infection, reflecting current hepatitis B virus infection, but a negative test cannot exclude hepatitis B virus infection. Hepatitis B surface antigen can persist for years, even for life, in asymptomatic carriers and chronic patients. Hepatitis B surface antigen itself is only antigenic and not infectious. Hepatitis B e antigen positive: Hepatitis B e antigen has a good correlation with hepatitis B virus DNA. The presence of hepatitis B e antigen indicates active viral replication and strong infectiousness, indicating that the patient is in a high infection low response period. Hepatitis B core antibody positive: Hepatitis B core antibody can be detected in almost all people infected with hepatitis B virus. Hepatitis B core antibody IgM is an antibody that appears earlier after HBV infection and is positive to indicate acute phase or acute attack of chronic hepatitis. Therefore, hepatitis B major triple yang refers to hepatitis B surface antigen, hepatitis B e antigen, hepatitis B core antibody three are positive, often suggest that the body virus replication is more active, more infectious.