Symptoms of extrapyramidal damage are mainly increased and decreased muscle tone, the preferred drugs should be selected according to the different causes, the common causes are drug side effects, Parkinson’s syndrome, hepatomegaly, etc. The preferred drugs include anticholinergics, dopamine agonists, and drugs to promote the excretion of copper. 1. Drug side effects: due to drugs such as antipsychotics such as chlorpromazine, fluphenazine, etc., the extrapyramidal symptoms caused by long-term use of drugs, discontinue the use of drugs or follow the doctor’s instructions to take. 2. Parkinson’s syndrome: preferred anticholinergics such as phenazopyridine or amantadine, and dopamine agonists such as pramipexole and piribedil. 3. Hepatomegaly: preferred to promote copper excretion, such as D-penicillamine, tretinoin. If you have extrapyramidal symptoms, it is recommended to go to the hospital in a timely manner, under the guidance of the doctor for standardized treatment, the above drugs should not be taken on their own, under the guidance of a doctor.