The pulse rate of a normal person is 60-100 times per minute and the heart rate is consistent, for some special people, such as athletes or the elderly, there will be occasional low pulse rate, in this case there is no obvious harm. However, for normal adults, if the pulse rate is low for a long time, it will cause damage to the corresponding target organ function, for example, long-term low pulse rate will cause inadequate blood supply to the heart, which will lead to chronic heart failure causing cardiogenic shock or even sudden death. Chronic low pulse rate can also cause insufficient blood supply to the corresponding target organs, such as cerebrovascular blood supply and lead to chronic cerebral infarction. Chronic low pulse rate can also cause endocrine dysfunction, such as aggravating primary diseases like hypothyroidism.