The most common causes of hot leg pain when standing up are localized infection, postherpetic neuralgia, sciatica, etc. If the patient’s symptoms continue to remain unimproved, it is recommended that he or she seeks medical attention in a timely manner. 1. Localized infections: If the skin on the legs of the patient is infected by bacteria due to trauma, boils, etc., and then an inflammatory reaction will occur, and in severe cases, abscesses will also occur, and the skin on the legs will be pulled when standing up, and then a hot and painful sensation will occur, and the patient needs to go to the hospital in time for the treatment of the wound. 2. Postherpetic neuralgia: varicella zoster virus is latent in the body, when the body’s immune system decreases, the virus may be activated to cause pain in the skin, the nature of the pain is more of a burning sensation, throbbing pain, activity is obvious when pulling, so stand up again may appear spicy pain in the legs. 3. Sciatica: lumbar disc herniation or bone spurs can stimulate the sciatic nerve, sciatica can involve the buttocks, the back of the thighs and calves, pain in the back of the outside, in the activities of the legs may produce spicy pain. If the symptoms of standing up leg pain have not been improved, it is recommended to go to the hospital for examination, to clarify the cause of the disease, targeted treatment.