April 12 is World Nose Day, do not underestimate the baby’s little nose, it is not only the starting point of the whistling tract, but also the most important olfactory organ to perceive smells. In addition, when we breathe in, the nose purifies the air we inhale and regulates its temperature and humidity. When we speak, the nose can play a role in supporting the pronunciation. Therefore, taking good care of the health of the little nose is the first step to a smooth whistling baby! The nasal cavity is the only organ of the body that does not close, is the lungs of the “air conditioning” and “filter”, 24 hours a day non-stop whistling air up to 15,000 liters, a lot of dust and bacteria in the air attached to the nasal vestibule, thus blocking the self-cleaning function of the nasal cavity. Caused by a large number of bacteria breeding, become a veritable garbage can, a great danger to human health. With the increasing severity of environmental pollution, many people’s nasal cavity gradually lose the function of filtering clean air, become a haven for bacteria, and directly lead to rhinitis, pharyngitis, bronchitis, pneumonia, pneumoconiosis, bacteriophageal lung and other diseases of the whistle, but also lead to reduced sense of smell, lack of oxygen supply to the brain, memory loss, reduced responsiveness, etc., seriously affecting the quality of life. According to authoritative data, about 90% of nasopharyngeal cancers are caused by the deterioration of untreated rhinitis. To draw public attention to inhalation health and nasal diseases, the World Health Organization has designated the second Saturday of April as World Nose Day – a worldwide awareness day for rhinological diseases. On this day, people take care of their own noses and those of their families by participating in activities such as scientific nose washing. The human nasal cavity has a complete layer of epithelial cells (including ciliated epithelial cells, cupped cells and basal cells) and a mucus blanket on its surface. These structures form an effective mucus cilia transport system, which is the first line of defense against attack by external pathogens. Containing a lysis layer and a gel layer, foreign bacteria, fungi, and allergens can be captured by the mucus layer. The oscillation of the cilia is mainly controlled by the gel layer and the cilia oscillate towards the nasopharynx to allow foreign bodies to be swallowed or spit out in the nasopharynx. Therefore, the functional state of cilia is closely related to the functional state of the nasal cavity. The purpose of nasal cleansing is to restore the cilia oscillation function, both physically and medically, to restore the normal physiological function of the nasal cavity against external pathogens. Under normal conditions, the cilia oscillate at a frequency of 12 times per second, and the nasal cavity can be cleared of harmful substances in about 15-20 minutes. Through more than 30 years of clinical practice on neonatology, I found that nasal rinsing is a very simple, economical and effective method to treat pediatric rhinitis, sinusitis, pediatric cough and pediatric bronchial asthma, which can significantly relieve patients’ nasal and sinus symptoms, and at the same time can reduce the dosage of antihistamine and other medication treatment, and can reduce bacterial drug resistance. Moreover, effective nasal irrigation can clean the nasal cavity and remove the stimulation of the nasal mucosa by the fungal mass, which is conducive to the stability of the internal environment of the nasal mucosa and can reduce the incidence of chronic rhinitis, sinusitis, asthma and other diseases. I have also found in my clinic that hypertonic saline nasal rinses can significantly improve patients’ symptoms and reduce the use of oral antihistamines. Therefore, I would recommend in my clinic that patients with seasonal allergic rhinitis apply hypertonic saline nasal rinses during pollen season. I have also found that the function of the ciliary system of patients with chronic sinusitis is significantly improved by nasal rinsing after endoscopy, and when combined with 3% hypertonic saline improves the rate of mucociliary glycoconjugate transport. In chronic sinusitis, effective nasal irrigation can reduce mucosal edema, reduce inflammatory cell infiltration and decrease cytokine concentration in interstitial fluid. In fact, postoperative nasal irrigation and topical steroid hormone nasal spray can consolidate the efficacy of endoscopic surgery. With the improvement of people’s living standard, the concept of pursuing a healthy and high-quality life has been deeply rooted, and nasal care has been paid more and more attention.