Autologous fat facial filler is to transplant fat from the abdomen or inner thighs to sunken or unfilled areas for the purpose of rejuvenation and cosmetic improvement. In the decades of clinical application, no serious complications or sequelae have been found, but a very small number of people may have problems such as hard nodes and infections. The reason is that although the incision of “autologous fat facial filler” is not large and is a minimally invasive surgery, it is not out of the scope of surgery. As the saying goes, surgery has risks, and autologous fat facial filler is no exception. It also has the first major problem faced by all surgeries – infection. Once infected, the area may appear red and swollen, which is only minor. If it is more serious, it will lead to pus and ulceration, which will eventually affect the appearance of our filler area and lead to unpredictable damage. There is a risk of infection in any surgery, but the risk of infection is controllable, so it is especially important to choose a proper hospital. Another side effect is: fat embolism. Fat embolism may cause pulmonary embolism, which may affect life; cerebral infarction, which may lead to hemiplegia and even loss of intelligence; embolism of the eye artery, which may lead to blindness, etc. Secondly, it is the unevenness that occurs after fat filling. There are 2 major reasons for the unevenness: 1. The problem of the doctor’s injection level If the doctor is not experienced, the level of his injection may be uneven, which may lead to the unevenness after the operation. 2, post-operative care Many candidates feel that this place on the face is a little high and that place is a little low after surgery. Should I press the high place to make it a little flatter? In fact, the swelling is often asymmetrical. At this time, if you press it too early, it may lead to excessive fat absorption or damage, which affects the final result and may appear uneven. There is another more common one: nodules or lumps (appear when large-capacity fat filling) When we need to fill large-capacity fat, such as buttock augmentation, the fat gathers too much; or the fat injection cavity is too concentrated during the injection process. It is possible that the fat in the core is not nourished by tissue fluid, and at this time it will gradually deactivate and liquefy, and finally form a cyst, or form a nodule or calcification, and this kind of mass may be found in our breast, buttocks or filler area. A similar situation can occur in the face. For example, postoperative local inflammation due to poor asepsis during surgery can cause the fat to liquefy and nodules and calcifications to appear. From the above-mentioned causes of side effects, most of them are caused by irregular operation of doctors or substandard operation environment.