Primary bronchial lung cancer (lung cancer for short) is one of the most common malignant tumors. Its incidence has been increasing year by year in recent years, and the incidence of non-small cell lung cancer (NSCLC) accounts for about 80% of all lung cancer cases. 2/3 of patients have lost the chance of surgery when diagnosed, i.e., they are stage IIIb-IV patients, whose median survival is only 8-10 months and need effective treatment to improve the quality of life and prolong the survival period. Chemotherapy plays an important role in the treatment of advanced NSCLC, but chemotherapy is often associated with toxic side effects of varying degrees, which affects its therapeutic effect. Therefore, chemotherapy side effects are an important factor for clinicians to consider when formulating chemotherapy release plans. Chinese medicine has made great progress in the prevention and treatment of chemotherapy toxic side effects and efficiency enhancement. It has been clinically shown that the combination of platinum can maximize the survival of patients with advanced NSCLC. However, due to the cytotoxicity of drugs, while killing tumor cells, normal cells are also damaged, and toxic side effects such as gastrointestinal reactions, bone marrow suppression, hepatic and renal toxicity, as well as decreased appetite, peripheral neurotoxicity and skin rash occur, thus causing a decrease in patients’ quality of life and Karnofsky score, and even causing patients’ rejection of chemotherapy. The clinical research has become a hot spot and development trend of tumor. According to the characteristics of Chinese medicine, the combination of Chinese and Western medicine can improve the anti-cancer effect, prolong the survival period and improve the quality of life for advanced malignant tumors. Addi injection is a compound dosage form made of traditional Chinese medicine, which is a non-cytotoxic drug composed of Ginseng, Astragalus, and Acanthopanax on the basis of Zanthopanax, a drug that removes blood stasis and disperses nodules to attack toxicity, and is added to support and cultivate the essence of traditional Chinese medicine. Research proves that zebularine in zebularine firstly inhibits protein synthesis of cancer cells, then affects DNA and RNA biosynthesis, and finally realizes inhibiting the growth and division of cancer cells; while the contained zebularine sodium can inhibit the DNA and RNA content of cancer cells and the infiltration of precursors, thus acting on the nucleic acid metabolism of cancer cells, then changing the morphology and function of cancer cells and killing cancer cells. It can also promote the differentiation of bone marrow hematopoietic stem cells to granulocytes-monocytes and increase white blood cells, thus having the characteristic of anti-cancer without bone marrow suppression. On the other hand, ginseng contains ginsenosides which have the effect of reducing the toxicity of anti-cancer drugs, it can promote the biosynthesis and metabolism of nucleic acid and protein in bone marrow, increase the division and proliferation of bone marrow cells, and is the leukocyte rebound of tumor patients. It also enhances the activity of macrophages, LAK cells and NK cells in combination with astragaloside and prunus saponin, and induces the production of interferon, interleukin and tumor necrosis factor, thus improving the immune function. It can be seen through the combination of Addi injection with chemotherapy that the herbal preparation can reduce the adverse effects of chemotherapy and also increase the efficacy and patient tolerance to the chemotherapy regimen, which can improve the quality of life and maximize the benefits for tumor patients.