Cold weather has an adverse effect on brain infarction, which can aggravate the signs and symptoms of the existing infarction and may also induce new brain infarction. Cold weather easily causes vasospasm, which can cause blood supply obstruction in the brain, and may cause cerebral ischemia and hypoxia, which may lead to ischemic necrosis and softening of the new limited brain tissue, or aggravate the ischemia and hypoxia of the original brain tissue. When the weather gets cold, patients with cerebral infarction should keep warm in time to prevent worsening of symptoms or new infarct foci. Patients with cerebral infarction can have a variety of triggering factors, mainly including seasonality, such as the weather becomes cold is an adverse effect, at the same time, also includes patients smoking, drinking and obesity, in addition, also includes patients with high blood lipids, hypertension, hyperglycemia and hyperhomocysteinemia.