As the name implies, Estradiol Digestrol Complex is a combination of estradiol and digestrol, so it contains both estrogen and progestin. It is effective in the treatment of perimenopausal syndrome, such as hot flashes, night sweats and insomnia, but the dosage and duration of the medication must be in accordance with medical advice. It also has some therapeutic value for women with declining ovarian function and abnormal uterine bleeding, post-operative uterine adhesions, and hormone replacement for frozen embryo transfer, etc. Generally, a course of 28 days is taken orally, and the next course is continued from the 29th day to establish an artificial cycle. It is not recommended for those who have breast cancer, endometrial cancer or serious medical and surgical diseases, and remember not to miss any dose during taking it.