Interarm inversions of chromosome 9 are more common. It occurs in up to 1% of the population. Since there is no significant loss of genetic material in the inverted chromosome and the carrier phenotype is normal, interarm inversions of chromosome 9 are generally considered to be a polymorphism and can be considered normal. It has also been reported that the inversion of chromosome 9 is a polymorphism only when it occurs in the subconstriction zone. If the inversion zone is beyond the subconstriction zone, it will form a unique inversion circle during the meiosis of germ cells according to the rule of pairing homologous chromosome segments with each other in gamete formation. After the odd exchange in the inversion circle, four different kinds of gametes can be formed. One is a normal chromosome, one is an inverted chromosome, and the other two can form two recombinant chromosomes with partial duplication and partial deletion due to the interchange of the inverted segment with the corresponding segment of another normal chromosome. After fertilization with normal gametes, the recombinant chromosomes cause imbalance of genetic material, deletion or duplication resulting in miscarriage, infertility or delivery of abnormal babies, causing poor reproductive history and fetal loss. However, the relationship between inter-arm inversions of chromosome 9 and disease remains unclear. From a genetic point of view, it can be assumed that carriers of interarm inversions of chromosome 9 cannot be considered chromosomal abnormalities and can conceive and give birth through IVF.