The phenomenon of coughing when lying down and not coughing when sitting up is mainly common for two reasons, one is cardiogenic asthma, often underlying heart disease leading to left heart failure, this time will cause pulmonary stasis, and when lying down the amount of return blood will increase, further aggravating the symptoms of pulmonary stasis, so it will lead to the appearance of cough. Another reason is that serious infection occurs in the lungs, and when lying down, the bronchial tree of the lungs will be compressed by the surrounding lung tissues, and inflammatory infection will occur, leading to bronchial stenosis, and then the compression of the lung tissues will aggravate the stenosis phenomenon and induce the appearance of cough. At this time, anti-inflammatory treatment is required, and depending on the type of infection, appropriate antibiotics or antiviral drugs are selected. Cough suppressants and phlegmolytic drugs, such as aminoglutethimide oral solution, pulmonary cough combination or aminoglutethimide hydrochloride, are also required. In the case of cardiogenic asthma, the underlying heart disease should be treated primarily to relieve the coughing symptoms.