Gynostemma can have different therapeutic effects when paired with different medications, so there is no such thing as the most effective pairing medication. Gynostemma is the whole herb of the plant Gynostemma gibbosum of the Cucurbitaceae family, which has the effects of strengthening the spleen, resolving phlegm, nourishing the heart and tranquilizing the mind (stabilizing the mind by nourishing the heart). It can be used to treat dry mouth and heartburn caused by injury of qi and yin; it can be used to treat lung dryness and cough when paired with Phellodendron Bark; it can be used to treat cough and phlegm caused by phlegm-dampness when paired with Semixia; and it can be used to treat insomnia and fatigue when paired with Poria. With different drugs, can play gibberellic acid different drug efficacy, so can not be too absolute that, which drug is the best with gibberellic acid, should be based on the patient’s type of evidence to choose. It should be chosen according to the patient’s condition. Patients with deficiency and cold conditions should not use this medicine. If patients need to use the drug, they should consult a traditional Chinese medicine practitioner to ensure the safety of the drug.