Tonsillitis is a common ENT disease. If the cause is a virus such as adenovirus or influenza virus, no treatment is usually needed and the symptoms can be relieved on their own. If it is due to acute bacterial infection, the more common bacteria are Staphylococcus aureus and Streptococcus haemolyticus, then second-generation cephalosporins and third-generation cephalosporins can be chosen for treatment, which are effective. If patients are allergic to cephalosporins, they can choose other types of antibiotics for treatment.1. Second-generation cephalosporins: Most patients can prefer second-generation cephalosporin treatment, more commonly used are cefaclor capsules, cefprozil dispersible tablets, cefuroxime tablets, etc., which can reduce tonsil congestion and swelling and relieve sore throat symptoms. The treatment cycle is usually about 1 week, and the overall treatment effect is good; 2. Third-generation cephalosporins: Some patients have more serious tonsillitis, with symptoms such as sore throat, fever, swallowing obstruction and poor breathing, and the treatment effect with second-generation cephalosporins is not good at this time. Usually you can choose third-generation cephalosporins, such as cefotaxime sodium for injection, cefixime capsule, cefoperazone sodium for injection, ceftazidime for injection, cefdinir dispersible tablets, etc. Compared to second-generation cephalosporins, their antibacterial effect is stronger and more effective for the treatment of severe inflammation; 3. Roxithromycin capsules. In addition, you can also choose quinolones, such as levofloxacin hydrochloride tablets, ciprofloxacin tablets, etc., also has a good anti-inflammatory effect. All of the above drugs are prescription drugs and need to be used under the guidance of a physician, and regular follow-ups are needed to observe the effects of treatment.