Knee squatting pain may be related to meniscus injury, osteoporosis and other reasons. 1. Meniscus injury: There are medial and lateral meniscus-shaped bones on the articular surface of tibia, called meniscus. The normal meniscus has the function of increasing the tibial condylar depression and lining the femoral epicondyle and epicondyle to increase the stability of the joint and cushion the shock. When rotational force, shear force, etc. lead to meniscus injury, it can cause knee pain, inability to straighten, swelling and other symptoms. 2. Osteoporosis: It is a systemic bone disease characterized by decreased bone mass, destruction of bone microstructure, increased bone fragility and easy fracture. It can be characterized by low back pain, bone pain caused by strenuous exercise, weight-bearing exercise and postural changes, and symptoms such as knee pain from squatting. Knee squatting pain may also be caused by knee sprains, etc. It is recommended to consult a doctor in time for a clear diagnosis and targeted treatment under the guidance of the doctor.