Chronic renal insufficiency needs to be examined by blood routine, urine routine, blood biochemistry and other tests. 1. Blood routine: usually suggests anemia, some patients have obvious anemia, most of them are normocytic anemia, normal or increased white blood cell count, normal or decreased platelets, and so on. 2. Urine routine: generally there are different differences between different primary diseases, patients with tubular injury can show decreased urine osmolality, increased quantitative urine protein, urine sediment examination shows many different types of red blood cells, white blood cells, epithelial cells and granular tubular pattern, of which the wax-like tubular pattern is the most meaningful. 3. Blood biochemistry: blood creatinine, urea nitrogen, cystatin C can be seen significantly increased, plasma albumin decreased, blood calcium decreased, blood phosphorus increased, blood potassium and blood sodium depending on the condition, carbon dioxide binding capacity decreased. 4. Other tests: urinary ultrasonography, X-ray urography, renal scanning and renal biopsy are also helpful in the diagnosis of etiology. Patients with chronic renal insufficiency should seek medical treatment from regular hospitals in time.