Segmental vitiligo has the potential to develop extensively. If the patient is not actively treated in the early stage of segmental vitiligo, the condition may be uncontrollable and develop extensively at a later stage. The pathogenesis of segmental vitiligo is not very clear at present. It usually occurs in children and may affect the development of the skin nerves of the patients. Segmental vitiligo usually progresses faster in the early stages and can be controlled by hormonal drugs such as prednisone. As the condition stabilizes, it can be treated by irradiating narrow-spectrum-UVB. If the lesions of vitiligo are stable and still not improved after treatment, it can be treated by epidermal transplantation. When the patient after the occurrence of segmental vitiligo, it is recommended to go to the regular hospital in a timely manner, under the guidance of professional doctors for active treatment.