Patients presenting with hematospermia should be treated differently depending on the cause of the capillary rupture. Patients with hematospermia due to capillary rupture may be due to excessive sexual life, inflammation, tumor, etc. Medications that can be used include levofloxacin, abiraterone, bicalutamide, or vesicoscopic flushing. 1. Excessive sexual life: patients who have frequent sexual intercourse will easily lead to the rupture of capillaries in the genital organs, which will result in hematospermia; patients should suspend sexual intercourse, and if conservative treatment is ineffective, they can take surgical treatment, such as vesicoscopy for flushing. 2. Inflammation: if the patient has prostatitis or seminal vesiculitis, the inflammation can lead to capillary fragility and hematospermia; at this time, the patient can take antibiotics such as levofloxacin, and the treatment cycle is usually 1~2 weeks; if the patient has old hematospermia and the medication is ineffective, the patient can be flushed through the vesiculoscopy. 3. Tumor: prostate tumor or seminal vesicle tumor can lead to abnormal congestion of reproductive organs and capillary rupture leading to hematospermia; at this time, we should focus on treating the primary disease, for example, taking abiraterone, bicalutamide, or radical prostate cancer surgery to remove the tumor. Patients with hematospermia should go to the hospital immediately to find the cause of the disease, and medications should be taken under the guidance of a doctor.