The best medication for nodules in the lungs depends mainly on the cause of the nodules in the lungs, the most common clinically is the formation of inflammatory pseudotumors due to inflammatory reactions. For example, due to bacterial infection, antibiotics such as penicillin, amoxicillin, clarithromycin, azithromycin, clindamycin, cefoperazone sulbactam sodium and other drugs can be chosen. If the pulmonary nodule is due to Mycobacterium tuberculosis infection causing pulmonary tuberculosis ball, a combination of anti-tuberculosis drugs such as isoniazid, rifampin, ethambutol, pyrazinamide, streptomycin, and levofloxacin should be chosen. If the pulmonary nodule is clearly cancerous through biopsy, anti-cancer drugs such as cisplatin and vincristine should be chosen for treatment at this time, and combined with surgery for the best efficacy.