You should not usually drink alcohol two hours after taking metformin, and drinking alcohol while taking metformin may increase the risk of lactic acidosis. Metformin is a hypoglycemic drug, which can help diabetics lower their blood sugar and keep it stable. However, metformin can also cause side effects, such as lactic acidosis and gastrointestinal reactions. Drinking alcohol may affect lactic acid metabolism and increase the likelihood of lactic acidosis. Metformin is more irritating to the gastrointestinal tract, and alcohol is equally irritating to the gastrointestinal tract. If you take metformin and drink alcohol at the same time, the gastrointestinal tract is doubly irritated, and the damage to the gastrointestinal tract will be even more severe. Therefore, it is best not to drink alcohol while taking Metformin. Patients should take metformin under the guidance of a doctor, not blindly use the drug.