Hypofractionated neck sarcoma is a malignant tumor that occurs in the neck, with tumor cells originating from mesenchymal tissues, with a morphology that differs greatly from that of normal cells, and with a high degree of malignancy. Sarcomas are malignant tumors originating from mesenchymal tissues, which include blood vessels, rhabdomyosarcoma, fat, bone, cartilage, and synovium, etc. There are more than 100 pathological subtypes of sarcomas, all of which are relatively rare. The degree of differentiation refers to the degree of similarity between cells and normal tissues in terms of morphology and behavior, etc. Usually, the degree of differentiation of malignant tumors has a negative correlation with the degree of malignancy, i.e., the lower the degree of differentiation, the greater the difference between the behavior and morphology of tumor cells and normal cells, and the greater the degree of malignancy of the tumor. Low-differentiated sarcoma of neck is a kind of serious malignant tumor, which needs timely treatment, otherwise, systemic metastasis may occur and endanger the life, it is recommended that patients go to the hospital as soon as possible, so as to make a clear diagnosis in time and be treated accordingly.