Zhu Sha An Shen Pill and Tian Wang Zhen Xin Wan have the effect of tranquilizing the mind when taken together, but it is not recommended to take the two together because both drugs contain Zhu Sha, which may lead to an overdose of Zhu Sha after being taken together or after a long period of time, thus causing a toxic reaction and harm to the body. Therefore, patients are advised to consult their doctors before use and follow medical advice. Zhu Sha An Shen Pill is mainly composed of Zhu Sha, Huang Lian, Di Huang, etc. It has the efficacy of clearing the heart and nourishing the blood, suppressing fright and tranquilizing the mind (using medicines of a heavy and calming nature to stabilize the mind), and is used for the treatment of irritation and heat in the chest (irritability and sultriness), palpitations (accelerated heartbeat often accompanied by heartburn), and restlessness, insomnia, and dreamlessness. It should not be used by those with insufficient heart qi and restlessness of the heart and mind. Tianwang Xinzhu Pill is mainly composed of Salvia miltiorrhiza, Radix Angelicae Sinensis, Acorus calamus, Radix et Rhizoma Ginseng, etc. It has the effect of nourishing Yin and nourishing Blood (nourishing the blood in the body), tonifying the heart and tranquilizing the mind, and is often used for treating deficiency of heart Yin, palpitations, forgetfulness, insomnia and excessive sleepiness, and dryness of stools. Caution should be exercised in cases of liver and kidney insufficiency.