Alkaline phosphatase is one of the biochemical tests that may be elevated due to pathological changes or physiological causes. Alkaline phosphatase is used to diagnose hepatobiliary and skeletal disorders and is an important indicator of extrahepatic biliary obstruction, intrahepatic space-occupying lesions and rickets. When elevated, it may be due to hepatobiliary diseases such as acute hepatitis; it may also be due to skeletal diseases such as deformational osteitis; and it may also be elevated in malignant tumors, uremia, and intestinal obstruction. All of the above are pathologic changes, and the occurrence of the above situations requires further improvement of relevant examinations in the hospital to clarify the diagnosis. Elevation may also occur during pregnancy, which is a special period of time when hormone secretion in the body is different from the usual, but elevated levels need to be taken seriously, except for pathologic factors. In conclusion, the occurrence of elevation should be taken seriously, check whether it is elevated or not, and if it is elevated, actively consult the hospital.